Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice

Heme oxygenase (HO) catalyzes the oxidation of heme to generate carbon monoxide (CO) and bilirubin. CO increases cellular levels of cGMP, which regulates vascular tone and smooth muscle development. Bilirubin is a potent antioxidant. Hypoxia increases expression of the inducible HO isoform (HO-1) bu...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Yet, Shaw-Fang, Perrella, Mark A., Layne, Matthew D., Hsieh, Chung-Ming, Maemura, Koji, Kobzik, Lester, Wiesel, Philippe, Christou, Helen, Kourembanas, Stella, Lee, Mu-En
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 1999
विषय:
Rapid Publication
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC408281/
https://ncbi.nlm.nih.gov/pubmed/10207174
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