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The Role of Heme Oxygenase-1 in Pulmonary Disease

Heme oxygenase (HO)-1, the inducible isoform of heme oxygenase, is a cytoprotective enzyme that plays a central role in the defense against oxidative and inflammatory insults in the lung. HO-1 catalyzes the degradation of heme, a potent oxidant, into biliverdin, iron, and carbon monoxide (CO). These...

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Detalles Bibliográficos
Main Authors: Fredenburgh, Laura E., Perrella, Mark A., Mitsialis, S. Alex
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176110/
https://ncbi.nlm.nih.gov/pubmed/16980551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0331TR
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