The Unfolded Protein Response and Chemical Chaperones Reduce Protein Misfolding and Colitis in Mice

BACKGROUND & AIMS: Endoplasmic reticulum (ER) stress has been associated with development of inflammatory bowel disease. We examined the effects of ER stress–induced chaperone response and the orally active chemical chaperones tauroursodeoxycholate (TUDCA) and 4-phenylbutyrate (PBA), which facil...

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Bibliografski detalji
Glavni autori: CAO, STEWART SIYAN, ZIMMERMANN, ELLEN M., CHUANG, BRANDY–MENGCHIEH, SONG, BENBO, NWOKOYE, ANOSIKE, WILKINSON, J. ERBY, EATON, KATHRYN A., KAUFMAN, RANDAL J.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751190/
https://ncbi.nlm.nih.gov/pubmed/23336977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.01.023
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