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Molecular chaperones are nanomachines that catalytically unfold misfolded and alternatively folded proteins

By virtue of their general ability to bind (hold) translocating or unfolding polypeptides otherwise doomed to aggregate, molecular chaperones are commonly dubbed “holdases”. Yet, chaperones also carry physiological functions that do not necessitate prevention of aggregation, such as altering the nat...

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Autors principals: Mattoo, Rayees U. H., Goloubinoff, Pierre
Format: Artigo
Idioma:Inglês
Publicat: Springer Basel 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131146/
https://ncbi.nlm.nih.gov/pubmed/24760129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-014-1627-y
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