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Molecular chaperones are nanomachines that catalytically unfold misfolded and alternatively folded proteins

By virtue of their general ability to bind (hold) translocating or unfolding polypeptides otherwise doomed to aggregate, molecular chaperones are commonly dubbed “holdases”. Yet, chaperones also carry physiological functions that do not necessitate prevention of aggregation, such as altering the nat...

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Библиографические подробности
Главные авторы: Mattoo, Rayees U. H., Goloubinoff, Pierre
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Basel 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131146/
https://ncbi.nlm.nih.gov/pubmed/24760129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-014-1627-y
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