FDG-PET imaging reveals local brain glucose utilization is altered by class I histone deacetylase inhibitors

The purpose of this work – the first of its kind - was to evaluate the impact of chronic selective histone deacetylase (HDAC) inhibitor treatment on brain activity using uptake of the radioligand (18)F-fluorodeoxyglucose and positron emission tomography ((18)FDG-PET). HDAC dysfunction and other epig...

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Detalhes bibliográficos
Main Authors: Schroeder, Frederick A., Chonde, Daniel B., Riley, Misha M., Moseley, Christian K., Granda, Michael L., Wilson, Colin M., Wagner, Florence F., Zhang, Yan-Ling, Gale, Jennifer, Holson, Edward B., Haggarty, Stephen J., Hooker, Jacob M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750730/
https://ncbi.nlm.nih.gov/pubmed/23810801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2013.06.016
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