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SH3-binding Protein 5 Mediates the Neuroprotective Effect of the Secreted Bioactive Peptide Humanin by Inhibiting c-Jun NH(2)-terminal Kinase

Humanin is a secreted bioactive peptide that suppresses cell toxicity caused by a variety of insults. The neuroprotective effect of Humanin against Alzheimer disease (AD)-related death is mediated by the binding of Humanin to its heterotrimeric Humanin receptor composed of ciliary neurotrophic recep...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Takeshita, Yuji, Hashimoto, Yuichi, Nawa, Mikiro, Uchino, Hiroyuki, Matsuoka, Masaaki
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750166/
https://ncbi.nlm.nih.gov/pubmed/23861391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.469692
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