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KCTD20, a relative of BTBD10, is a positive regulator of Akt
BACKGROUND: BTBD10 binds to Akt and protein phosphatase 2A (PP2A) and inhibits the PP2A-mediated dephosphorylation of Akt, thereby keeping Akt activated. Previous studies have suggested that BTBD10 plays an important role in preventing motor neuronal death and accelerating the growth of pancreatic b...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BioMed Central
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3827329/ https://ncbi.nlm.nih.gov/pubmed/24156551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-14-27 |
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