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CHIP Regulates AKT/FoxO/Bim Signaling in MCF7 and MCF10A Cells

A number of studies have shown that apoptosis resistance can be observed in multiple human tumors; however the detailed mechanism remains unclear. In the present study, we demonstrated that the abnormal overexpression of the C terminus of Hsc70-interacting protein (CHIP) induced apoptosis resistance...

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Detalhes bibliográficos
Main Authors: Lv, Yanrong, Song, Shanshan, Zhang, Kai, Gao, Haidong, Ma, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869759/
https://ncbi.nlm.nih.gov/pubmed/24376685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083312
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