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RETRACTED ARTICLE: Idelalisib promotes Bim-dependent apoptosis through AKT/FoxO3a in hepatocellular carcinoma

Idelalisib, a selective PI3Kδ inhibitor, has been approved by the FDA for chronic lymphocytic leukemia/small lymphocytic lymphoma treatment and for follicular lymphoma treatment when combined with rituximab. However, the mechanisms of effective action of idelalisib in hepatocellular carcinoma (HCC)...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Yue, Dan, Sun, Xun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141589/
https://ncbi.nlm.nih.gov/pubmed/30224718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0960-8
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