Reduced expression of BTBD10, an Akt activator, leads to motor neuron death

BTBD10, an Akt interactor, activates Akt by decreasing the protein phosphatase 2A-mediated dephosphorylation and inactivation of Akt. Overexpression of BTBD10 suppresses motor neuron death that is induced by a familial amyotrophic lateral sclerosis (ALS)-linked superoxide dismutase 1 (SOD1) mutant,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Nawa, M, Kage-Nakadai, E, Aiso, S, Okamoto, K, Mitani, S, Matsuoka, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392628/
https://ncbi.nlm.nih.gov/pubmed/22388351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.19
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados