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DNA-N-Glycosylases Process Novel O-Glycosidic Sites in DNA()

After hydrolyzing the N-glycosyl bond between a damaged base and C1' of a deoxyribosyl moiety of DNA, human alkyladenine DNA glycosylase (AAG) and E. coli 3-methyladenine DNA glycosylase II (AlkA) bind tightly to their abasic DNA products, potentially protecting these reactive species. Here we...

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Autori principali: Admiraal, Suzanne J., O'Brien, Patrick J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750082/
https://ncbi.nlm.nih.gov/pubmed/23688261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400218j
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