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Humanized mice for immune system investigation: progress, promise and challenges

PREFACE: Significant advances in our understanding of the in vivo functions of human cells, tissues and immune systems have resulted from the development of mouse strains that are based on severely immunodeficient mice expressing mutations in the interleukin-2 (IL-2) receptor common γ-chain locus. T...

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Bibliografske podrobnosti
Main Authors: Shultz, Leonard D., Brehm, Michael A., Garcia, J. Victor, Greiner, Dale L.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749872/
https://ncbi.nlm.nih.gov/pubmed/23059428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3311
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