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Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice
BACKGROUND: Currently used mouse models fail to fully reflect human immunity to tuberculosis (TB), which hampers progress in research and vaccine development. Bone marrow-liver-thymus (BLT) mice, generated by engrafting human fetal liver, thymus, and hematopoietic stem cells in severely immunodefici...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3924189/ https://ncbi.nlm.nih.gov/pubmed/24313934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-14-53 |
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