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Advancing Animal Models of Human Type 1 Diabetes by Engraftment of Functional Human Tissues in Immunodeficient Mice

Despite decades of studying rodent models of type 1 diabetes (T1D), no therapy capable of preventing or curing T1D has successfully been translated from rodents to humans. This inability to translate otherwise promising therapies to clinical settings likely resides, to a major degree, from significa...

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Detalhes bibliográficos
Main Authors: Brehm, Michael A., Powers, Alvin C., Shultz, Leonard D., Greiner, Dale L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331686/
https://ncbi.nlm.nih.gov/pubmed/22553498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a007757
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