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Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells

Immunodeficient mice are being used as recipients of human hematopoietic stem cells (HSC) for in vivo analyses of human immune system development and function. The development of several stocks of immunodeficient Prkdc(scid) (scid), or recombination activating 1 or 2 gene (Rag1 or Rag2) knockout mic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Methods Mol Biol
Prif Awduron: Hasgur, Suheyla, Aryee, Ken Edwin, Shultz, Leonard D., Greiner, Dale L., Brehm, Michael A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268072/
https://ncbi.nlm.nih.gov/pubmed/27150084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3661-8_4
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