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Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells
Immunodeficient mice are being used as recipients of human hematopoietic stem cells (HSC) for in vivo analyses of human immune system development and function. The development of several stocks of immunodeficient Prkdc(scid) (scid), or recombination activating 1 or 2 gene (Rag1 or Rag2) knockout mic...
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| Publié dans: | Methods Mol Biol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5268072/ https://ncbi.nlm.nih.gov/pubmed/27150084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3661-8_4 |
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