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Immunodeficient mouse model for human hematopoietic stem cell engraftment and immune system development

Immunodeficient mice engrafted with human immune systems provide an exciting model to study human immunobiology in an in vivo setting without placing patients at risk. The essential parameter for creation of these “humanized models” is engraftment of human hematopoietic stem cells (HSC) that will al...

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Detalles Bibliográficos
Publicado en:Methods Mol Biol
Main Authors: Aryee, Ken-Edwin, Shultz, Leonard D., Brehm, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476265/
https://ncbi.nlm.nih.gov/pubmed/25062635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-1133-2_18
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