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Immunodeficient mouse model for human hematopoietic stem cell engraftment and immune system development

Immunodeficient mice engrafted with human immune systems provide an exciting model to study human immunobiology in an in vivo setting without placing patients at risk. The essential parameter for creation of these “humanized models” is engraftment of human hematopoietic stem cells (HSC) that will al...

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Détails bibliographiques
Publié dans:Methods Mol Biol
Auteurs principaux: Aryee, Ken-Edwin, Shultz, Leonard D., Brehm, Michael A.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476265/
https://ncbi.nlm.nih.gov/pubmed/25062635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-1133-2_18
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