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Humanized mice for immune system investigation: progress, promise and challenges

PREFACE: Significant advances in our understanding of the in vivo functions of human cells, tissues and immune systems have resulted from the development of mouse strains that are based on severely immunodeficient mice expressing mutations in the interleukin-2 (IL-2) receptor common γ-chain locus. T...

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Bibliografiske detaljer
Main Authors: Shultz, Leonard D., Brehm, Michael A., Garcia, J. Victor, Greiner, Dale L.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749872/
https://ncbi.nlm.nih.gov/pubmed/23059428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3311
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