Endothelial human dihydrofolate reductase low activity limits vascular tetrahydrobiopterin recycling

Documenti analoghi

• Tetrahydrobiopterin, Superoxide and Vascular Dysfunction
  di: Vásquez-Vivar, Jeannette
  Pubblicazione: (2009)
• Increasing Tetrahydrobiopterin in Cardiomyocytes Adversely Affects Cardiac Redox State and Mitochondrial Function Independently of Changes in NO Production
  di: Sethumadhavan, Savitha, et al.
  Pubblicazione: (2016)
• The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: an EPR spin trapping study.
  di: Vásquez-Vivar, Jeannette, et al.
  Pubblicazione: (2002)
• Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency
  di: Crabtree, Mark J., et al.
  Pubblicazione: (2011)
• Cell type-specific recycling of tetrahydrobiopterin by dihydrofolate reductase explains differential effects of 7,8-dihydrobiopterin on endothelial nitric oxide synthase uncoupling
  di: Schmidt, Kurt, et al.
  Pubblicazione: (2014)