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Tetrahydrobiopterin, Superoxide and Vascular Dysfunction
(6R)-5,6,7,8-Tetrahydrobiopterin (BH(4)) is an endogenously produced pterin that is found widely distributed in mammalian tissues. BH(4) works as a cofactor of aromatic amino acid hydroxylases and nitric oxide synthases. In the vasculature a deficit of BH(4) is implicated in the mechanisms of severa...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852262/ https://ncbi.nlm.nih.gov/pubmed/19628033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.07.024 |
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