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Tetrahydrobiopterin in the Prevention of Hypertonia in Hypoxic Fetal Brain

OBJECTIVE: Tetrahydrobiopterin (BH(4)) deficiency is one of the causes of dystonia at birth. We hypothesized that BH(4) is a developmental factor determining vulnerability of the immature fetal brain to hypoxic-ischemic injury and subsequent motor deficits in newborns. METHODS: Pregnant rabbits were...

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Detalhes bibliográficos
Main Authors: Vásquez-Vivar, Jeannette, Whitsett, Jennifer, Derrick, Matthew, Ji, Xinhai, Yu, Lei, Tan, Sidhartha
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785106/
https://ncbi.nlm.nih.gov/pubmed/19798726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21738
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