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Developmental Susceptibility of Neurons to Transient Tetrahydrobiopterin Insufficiency and Antenatal Hypoxia-Ischemia in Fetal Rabbits

Tetrahydrobiopterin (BH(4)) is important for normal brain development as congenital BH(4) deficiencies manifest movement disorders at different childhood ages. BH(4) transitions from very low levels in fetal brains to higher ‘adult’ levels postnatally, with the highest levels in the thalamus. Matern...

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Detalhes bibliográficos
Main Authors: Yu, Lei, Vásquez-Vivar, Jeannette, Jiang, Rugang, Luo, Kehuan, Derrick, Matthew, Tan, Sidhartha
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945116/
https://ncbi.nlm.nih.gov/pubmed/24316196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.11.026
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