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Developmental Susceptibility of Neurons to Transient Tetrahydrobiopterin Insufficiency and Antenatal Hypoxia-Ischemia in Fetal Rabbits

Tetrahydrobiopterin (BH(4)) is important for normal brain development as congenital BH(4) deficiencies manifest movement disorders at different childhood ages. BH(4) transitions from very low levels in fetal brains to higher ‘adult’ levels postnatally, with the highest levels in the thalamus. Matern...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yu, Lei, Vásquez-Vivar, Jeannette, Jiang, Rugang, Luo, Kehuan, Derrick, Matthew, Tan, Sidhartha
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945116/
https://ncbi.nlm.nih.gov/pubmed/24316196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.11.026
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