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Single-Molecule Measurements of Transient Biomolecular Complexes through Microfluidic Dilution

[Image: see text] Single-molecule confocal microscopy experiments require concentrations which are low enough to guarantee that, on average, less than one single molecule resides in the probe volume at any given time. Such concentrations are, however, significantly lower than the dissociation consta...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Horrocks, Mathew H., Rajah, Luke, Jönsson, Peter, Kjaergaard, Magnus, Vendruscolo, Michele, Knowles, Tuomas P. J., Klenerman, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2013
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748451/
https://ncbi.nlm.nih.gov/pubmed/23782428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac4010875
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