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Single-Molecule Measurements of Transient Biomolecular Complexes through Microfluidic Dilution

[Image: see text] Single-molecule confocal microscopy experiments require concentrations which are low enough to guarantee that, on average, less than one single molecule resides in the probe volume at any given time. Such concentrations are, however, significantly lower than the dissociation consta...

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Detalhes bibliográficos
Main Authors: Horrocks, Mathew H., Rajah, Luke, Jönsson, Peter, Kjaergaard, Magnus, Vendruscolo, Michele, Knowles, Tuomas P. J., Klenerman, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748451/
https://ncbi.nlm.nih.gov/pubmed/23782428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac4010875
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