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A Microfluidic Approach for Investigating the Temperature Dependence of Biomolecular Activity with Single-Molecule Resolution

We present a microfluidic approach for single-molecule studies of the temperature-dependent behavior of biomolecules, using a platform that combines microfluidic sample handling, on-chip temperature control, and total internal reflection fluorescence (TIRF) microscopy of surface-immobilized biomolec...

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Detalhes bibliográficos
Main Authors: Wang, Bin, Ho, Joseph, Fei, Jingyi, Gonzalez, Ruben L., Lin, Qiao
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766768/
https://ncbi.nlm.nih.gov/pubmed/20981364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0lc00157k
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