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Single-Molecule Measurements of Transient Biomolecular Complexes through Microfluidic Dilution

[Image: see text] Single-molecule confocal microscopy experiments require concentrations which are low enough to guarantee that, on average, less than one single molecule resides in the probe volume at any given time. Such concentrations are, however, significantly lower than the dissociation consta...

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Main Authors: Horrocks, Mathew H., Rajah, Luke, Jönsson, Peter, Kjaergaard, Magnus, Vendruscolo, Michele, Knowles, Tuomas P. J., Klenerman, David
格式: Artigo
語言:Inglês
出版: American Chemical Society 2013
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748451/
https://ncbi.nlm.nih.gov/pubmed/23782428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac4010875
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