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Single-Molecule Measurements of Transient Biomolecular Complexes through Microfluidic Dilution

[Image: see text] Single-molecule confocal microscopy experiments require concentrations which are low enough to guarantee that, on average, less than one single molecule resides in the probe volume at any given time. Such concentrations are, however, significantly lower than the dissociation consta...

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Hlavní autoři: Horrocks, Mathew H., Rajah, Luke, Jönsson, Peter, Kjaergaard, Magnus, Vendruscolo, Michele, Knowles, Tuomas P. J., Klenerman, David
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2013
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748451/
https://ncbi.nlm.nih.gov/pubmed/23782428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac4010875
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