Critical role for the docking-protein FRS2α in FGF receptor-mediated signal transduction pathways

The docking protein FRS2α has been implicated as a mediator of signaling via fibroblast growth factor receptors (FGFRs). We have demonstrated that targeted disruption of FRS2α gene causes severe impairment in mouse development resulting in embryonal lethality at E7.0–E7.5. Experiments with FRS2α-def...

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Detaylı Bibliyografya
Asıl Yazarlar: Hadari, Y. R., Gotoh, N., Kouhara, H., Lax, I., Schlessinger, J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2001
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC37478/
https://ncbi.nlm.nih.gov/pubmed/11447289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161259898
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