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The docking protein FRS2α is a critical regulator of VEGF receptors signaling
Vascular endothelial growth factors (VEGFs) signal via their cognate receptor tyrosine kinases designated VEGFR1-3. We report that the docking protein fibroblast growth factor receptor substrate 2 (FRS2α) plays a critical role in cell signaling via these receptors. In vitro FRS2α regulates VEGF-A an...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992672/ https://ncbi.nlm.nih.gov/pubmed/24706887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404545111 |
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