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Critical role for the docking-protein FRS2α in FGF receptor-mediated signal transduction pathways
The docking protein FRS2α has been implicated as a mediator of signaling via fibroblast growth factor receptors (FGFRs). We have demonstrated that targeted disruption of FRS2α gene causes severe impairment in mouse development resulting in embryonal lethality at E7.0–E7.5. Experiments with FRS2α-def...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC37478/ https://ncbi.nlm.nih.gov/pubmed/11447289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161259898 |
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