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Donor B cells in Transplants Augment Clonal Expansion and Survival of Pathogenic CD4(+) T cells That Mediate Autoimmune-like Chronic GVHD
We reported that both donor CD4(+) T and B cells in transplants were required for induction of an autoimmune-like chronic graft versus host disease (cGVHD) in a murine model of DBA/2 donor to BALB/c recipient, but mechanisms whereby donor B cells augment cGVHD pathogenesis remain unknown. Here, we r...
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| Autors principals: | , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3746987/ https://ncbi.nlm.nih.gov/pubmed/22649197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200677 |
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