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Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases
Interferons (IFNs) are cytokines with powerful immunomodulatory and antiviral properties, but less is known about how they induce cell death. Here, we show that both type I (α/β) and type II (γ) IFNs induce precipitous receptor-interacting protein (RIP)1/RIP3 kinase-mediated necrosis when the adapto...
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| Glavni autori: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3746924/ https://ncbi.nlm.nih.gov/pubmed/23898178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301218110 |
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