NF-κB Inhibition by Bortezomib Permits Interferon-γ-Activated RIP1 Kinase-Dependent Necrosis in Renal Cell Carcinoma

Advanced renal cell carcinoma (RCC) is an invariably fatal cancer. Currently, small-molecule inhibitors that target cell-growth, angiogenesis, or nutrient-sensing pathways represent the primary pharmacological interventions for this disease, but these inhibitors only delay tumor progression and are...

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Detalhes bibliográficos
Main Authors: Thapa, Roshan J., Chen, Peirong, Cheung, Mitchell, Nogusa, Shoko, Pei, Jianming, Peri, Suraj, Testa, Joseph R., Balachandran, Siddharth
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746800/
https://ncbi.nlm.nih.gov/pubmed/23657944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-1010
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