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Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation

Acute myeloid leukemia (AML) induces bone marrow (BM) failure in patients, predisposing them to life-threatening infections and bleeding. The mechanism by which AML mediates this complication is unknown but one widely accepted explanation is that AML depletes the BM of hematopoietic stem cells (HSCs...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Miraki-Moud, Farideh, Anjos-Afonso, Fernando, Hodby, Katharine A., Griessinger, Emmanuel, Rosignoli, Guglielmo, Lillington, Debra, Jia, Li, Davies, Jeff K., Cavenagh, Jamie, Smith, Matthew, Oakervee, Heather, Agrawal, Samir, Gribben, John G., Bonnet, Dominique, Taussig, David C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746910/
https://ncbi.nlm.nih.gov/pubmed/23901108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301891110
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