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Rational design and generation of recombinant control reagents for bispecific antibodies through CDR mutagenesis
Developments in the field of bispecific antibodies have progressed rapidly in recent years, particularly in their potential role for the treatment of malignant disease. However, manufacturing stable molecules has proven to be costly and time-consuming, which in turn has hampered certain aspects of p...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3746479/ https://ncbi.nlm.nih.gov/pubmed/23806556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2013.06.003 |
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