A miR-34a-SIRT6 axis in the squamous cell differentiation network

Squamous cell carcinomas (SCCs) are highly heterogeneous tumours, resulting from deranged expression of genes involved in squamous cell differentiation. Here we report that microRNA-34a (miR-34a) functions as a novel node in the squamous cell differentiation network, with SIRT6 as a critical target....

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Detalhes bibliográficos
Main Authors: Lefort, Karine, Brooks, Yang, Ostano, Paola, Cario-André, Muriel, Calpini, Valérie, Guinea-Viniegra, Juan, Albinger-Hegyi, Andrea, Hoetzenecker, Wolfram, Kolfschoten, Ingrid, Wagner, Erwin F, Werner, Sabine, Dotto, Gian Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746195/
https://ncbi.nlm.nih.gov/pubmed/23860128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.156
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