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A miR-34a-SIRT6 axis in the squamous cell differentiation network

Squamous cell carcinomas (SCCs) are highly heterogeneous tumours, resulting from deranged expression of genes involved in squamous cell differentiation. Here we report that microRNA-34a (miR-34a) functions as a novel node in the squamous cell differentiation network, with SIRT6 as a critical target....

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Bibliografiska uppgifter
Huvudupphovsmän: Lefort, Karine, Brooks, Yang, Ostano, Paola, Cario-André, Muriel, Calpini, Valérie, Guinea-Viniegra, Juan, Albinger-Hegyi, Andrea, Hoetzenecker, Wolfram, Kolfschoten, Ingrid, Wagner, Erwin F, Werner, Sabine, Dotto, Gian Paolo
Materialtyp: Artigo
Språk:Inglês
Publicerad: European Molecular Biology Organization 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746195/
https://ncbi.nlm.nih.gov/pubmed/23860128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.156
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