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The HHM Motif at the CuH-site of Peptidylglycine Monooxygenase is a pH-Dependent Conformational Switch

Peptidylglycine monooxygenase is a copper-containing enzyme which catalyzes the amidation of neuropeptide hormones, the first step of which is the conversion of a glycine-extended pro-peptide to its α-hydroxyglcine intermediate. The enzyme contains two mononuclear Cu centers termed CuM (ligated to i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kline, Chelsey D., Mayfield, Mary, Blackburn, Ninian J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746079/
https://ncbi.nlm.nih.gov/pubmed/23530865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4002248
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