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The HHM Motif at the CuH-site of Peptidylglycine Monooxygenase is a pH-Dependent Conformational Switch
Peptidylglycine monooxygenase is a copper-containing enzyme which catalyzes the amidation of neuropeptide hormones, the first step of which is the conversion of a glycine-extended pro-peptide to its α-hydroxyglcine intermediate. The enzyme contains two mononuclear Cu centers termed CuM (ligated to i...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3746079/ https://ncbi.nlm.nih.gov/pubmed/23530865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4002248 |
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