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pH-Regulated Metal-Ligand Switching in the HM Loop of ATP7A: A New Paradigm for Metal Transfer Chemistry
Cuproproteins such as PHM and DBM mature in late endosmal vesicles of the mammalian secretory pathway where changes in vesicle pH are employed for sorting and post-translational processing. Colocation with the P1B-type ATPase ATP7A suggests that the latter is the source of copper, and supports a mec...
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| Publicado en: | Metallomics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4981546/ https://ncbi.nlm.nih.gov/pubmed/27242196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6mt00062b |
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