The Lumenal Loop Met(672)–Pro(707) of Copper-transporting ATPase ATP7A Binds Metals and Facilitates Copper Release from the Intramembrane Sites

The copper-transporting ATPase ATP7A has an essential role in human physiology. ATP7A transfers the copper cofactor to metalloenzymes within the secretory pathway; inactivation of ATP7A results in an untreatable neurodegenerative disorder, Menkes disease. Presently, the mechanism of ATP7A-mediated c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Barry, Amanda N., Otoikhian, Adenike, Bhatt, Sujata, Shinde, Ujwal, Tsivkovskii, Ruslan, Blackburn, Ninian J., Lutsenko, Svetlana
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2011
Gaiak:
Membrane Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143623/
https://ncbi.nlm.nih.gov/pubmed/21646353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.229039
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak