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Binding of Copper and Silver to Single-Site Variants of Peptidylglycine Monooxygenase Reveals the Structure and Chemistry of the Individual Metal Centers

[Image: see text] Peptidylglycine monooxygenase (PHM) catalyzes the final step in the biosynthesis of amidated peptides that serve as important signaling molecules in numerous endocrine pathways. The catalytic mechanism has attracted much attention because of a number of unique attributes, including...

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Bibliografiske detaljer
Main Authors: Chauhan, Shefali, Kline, Chelsey D., Mayfield, Mary, Blackburn, Ninian J.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985755/
https://ncbi.nlm.nih.gov/pubmed/24471980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4015264
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