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Stopped-Flow Studies of the Reduction of the Copper Centers Suggest a Bifurcated Electron Transfer Pathway in Peptidylglycine Monooxygenase()

PHM is a dicopper enzyme that plays a vital role in the amidation of glycine extended pro-peptides. One of the crucial aspects of its chemistry is the transfer of two electrons from an electron-storing and transferring site (CuH) to the oxygen binding site and catalytic center (CuM) over a distance...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochemistry
Hauptverfasser: Chauhan, Shefali, Hosseinzadeh, Parisa, Lu, Yi, Blackburn, Ninian J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879618/
https://ncbi.nlm.nih.gov/pubmed/26982589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00061
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