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A Genetically Encoded Acrylamide Functionality
N(ε)-acryloyl-L-lysine, a noncanonical amino acid with an electron deficient olefin, is genetically encoded in Escherichia coli using a pyrrolysyl-tRNA synthetase mutant in coordination with [Formula: see text]. The acrylamide moiety is stable in cells, whereas it is active enough to perform a diver...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3746000/ https://ncbi.nlm.nih.gov/pubmed/23735044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400267m |
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