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Extinction of Hepatitis C Virus by Ribavirin in Hepatoma Cells Involves Lethal Mutagenesis

Lethal mutagenesis, or virus extinction produced by enhanced mutation rates, is under investigation as an antiviral strategy that aims at counteracting the adaptive capacity of viral quasispecies, and avoiding selection of antiviral-escape mutants. To explore lethal mutagenesis of hepatitis C virus...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ortega-Prieto, Ana M., Sheldon, Julie, Grande-Pérez, Ana, Tejero, Héctor, Gregori, Josep, Quer, Josep, Esteban, Juan I., Domingo, Esteban, Perales, Celia
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745404/
https://ncbi.nlm.nih.gov/pubmed/23976977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071039
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