Lataa...
Rare haplotype load as marker for lethal mutagenesis
RNA viruses replicate with a template-copying fidelity, which lies close to an extinction threshold. Increases of mutation rate by nucleotide analogues can drive viruses towards extinction. This transition is the basis of an antiviral strategy termed lethal mutagenesis. We have introduced a new dive...
Tallennettuna:
| Julkaisussa: | PLoS One |
|---|---|
| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2018
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6169937/ https://ncbi.nlm.nih.gov/pubmed/30281674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204877 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|