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Lethal Mutagenesis of Hepatitis C Virus Induced by Favipiravir
Lethal mutagenesis is an antiviral approach that consists in extinguishing a virus by an excess of mutations acquired during replication in the presence of a mutagen. Here we show that favipiravir (T-705) is a potent mutagenic agent for hepatitis C virus (HCV) during its replication in human hepatom...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5068784/ https://ncbi.nlm.nih.gov/pubmed/27755573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164691 |
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