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Arenaviruses and Lethal Mutagenesis. Prospects for New Ribavirin-based Interventions

Lymphocytic choriomeningitis virus (LCMV) has contributed to unveil some of the molecular mechanisms of lethal mutagenesis, or loss of virus infectivity due to increased mutation rates. Here we review these developments, and provide additional evidence that ribavirin displays a dual mutagenic and in...

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Detalhes bibliográficos
Main Authors: Moreno, Héctor, Grande-Pérez, Ana, Domingo, Esteban, Martín, Verónica
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509673/
https://ncbi.nlm.nih.gov/pubmed/23202505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v4112786
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