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Arenaviruses and Lethal Mutagenesis. Prospects for New Ribavirin-based Interventions

Lymphocytic choriomeningitis virus (LCMV) has contributed to unveil some of the molecular mechanisms of lethal mutagenesis, or loss of virus infectivity due to increased mutation rates. Here we review these developments, and provide additional evidence that ribavirin displays a dual mutagenic and in...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Moreno, Héctor, Grande-Pérez, Ana, Domingo, Esteban, Martín, Verónica
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509673/
https://ncbi.nlm.nih.gov/pubmed/23202505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v4112786
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