Cyclin-dependent Kinase 1-dependent Phosphorylation of cAMP Response Element-binding Protein Decreases Chromatin Occupancy

The cyclic AMP response element-binding protein (CREB) initiates transcriptional responses to a wide variety of stimuli. CREB activation involves its phosphorylation on Ser-133, which promotes interaction between the CREB kinase-inducible domain (KID) and the KID-interacting domain of the transcript...

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Detalhes bibliográficos
Main Authors: Trinh, Anthony T., Kim, Sang Hwa, Chang, Hae-yoon, Mastrocola, Adam S., Tibbetts, Randal S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745323/
https://ncbi.nlm.nih.gov/pubmed/23814058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.464057
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